Sample Size Determination for Independent Outcomes Introduction Precision Analysis Power Analysis Sample Size Determination for Clustered Outcomes Introduction One-Sample Clustered Continuous Outcomes One-Sample Clustered Binary Outcomes Two-Sample Clustered Continuous Outcomes Two-Sample Clustered Binary Outcomes Stratified Cluster Randomization for Binary Outcomes Nonparametric Approach for One-Sample Clustered Binary Outcomes Sample Size Determination for Repeated Measurement Outcomes Using Summary Statistics Introduction Information Needed for Sample Size Estimation Summary Statistics Sample Size Determination for Correlated Outcome Measurements Using GEE Motivation Review of GEE Compare the Slope for a Continuous Outcome Test the TAD for a Continuous Outcome Compare the Slope for a Binary Outcome Test the TAD for a Binary Outcome Compare the Slope for a Count Outcome Test the TAD for a Count Outcome Sample Size Determination for Correlated Outcomes from Two-Level Randomized Clinical Trials Introduction Statistical Models for Continuous Outcomes Testing Main Effects Two Level Longitudinal Designs: Testing Slope Differences Cross-Sectional Factorial Designs: Interactions between Treatments Longitudinal Factorial Designs: Treatment Effects on Slopes Sample Sizes for Binary Outcomes Sample Size Determination for Correlated Outcomes from Three Level Randomized Clinical Trials Introduction Statistical Model for Continuous Outcomes Testing Main Effects Testing Slope Differences Cross-Sectional Factorial Designs: Interactions between Treatments Longitudinal Factorial Designs: Treatment Effects on Slopes Sample Sizes for Binary Outcomes Further Readings appear at the end of each chapter. g GEE Motivation Review of GEE Compare the Slope for a Continuous Outcome Test the TAD for a Continuous Outcome Compare the Slope for a Binary Outcome Test the TAD for a Binary Outcome Compare the Slope for a Count Outcome Test the TAD for a Count Outcome Sample Size Determination for Correlated Outcomes from Two-Level Randomized Clinical Trials Introduction Statistical Models for Continuous Outcomes Testing Main Effects Two Level Longitudinal Designs: Testing Slope Differences Cross-Sectional Factorial Designs: Interactions between Treatments Longitudinal Factorial Designs: Treatment Effects on Slopes Sample Sizes for Binary Outcomes Sample Size Determination for Correlated Outcomes from Three Level Randomized Clinical Trials Introduction Statistical Model for Continuous Outcomes Testing Main Effects Testing Slope Differences Cross-Sectional Factorial Designs: Interactions between Treatments Longitudinal Factorial Designs: Treatment Effects on Slopes Sample Sizes for Binary Outcomes Further Readings appear at the end of each chapter. ls Introduction Statistical Model for Continuous Outcomes Testing Main Effects Testing Slope Differences Cross-Sectional Factorial Designs: Interactions between Treatments Longitudinal Factorial Designs: Treatment Effects on Slopes Sample Sizes for Binary Outcomes Further Readings appear at the end of each chapter.