This Handbook comes at a critical moment in education, as generative AI rapidly transforms learning environments and creative processes. By bringing together leading international scholars and emerging voices, the volume aims to provide a comprehensive resource that will shape the future of AI in education across various contexts. The need for this Handbook arises from rapid advancements in generative AI and their implications for human creativity in education. While existing literature often explores AI and creativity in education as separate topics, there is a significant gap in understanding the complex interplay between AI and human creativity, particularly as it relates to human agency, creative teaching, and learning. This Handbook addresses this gap by providing a comprehensive and critical examination of the opportunities and challenges presented by AI for nurturing and fostering creativity in learners of all ages. This Handbook covers the multifaceted relationship between human creativity and AI, examining the potential of AI to serve as both a tool for enhancing creative expression and a catalyst for reimagining pedagogical approaches. It will also address ethical considerations and unintended consequences when using GenAI to augment human creativity in education, such as the potential for bias in AI and the importance of fostering human agency in creative processes, ensuring a balanced and nuanced perspective on the integration of AI in education.