"For a medical student or other health professional, first encountering a major field of medical knowledge is a daunting prospect. Opening up a 1500 textbook to grapple with assigned reading leaves one with a desperate feeling of helplessness, that one can ever become a medical practitioner with any degree of competence. With strong memories still of being that student, what is needed is a wise teacher saying, ''this is what you need to know.'' The same is true for being a resident or fellow in laboratory medicine; now you really need to know the material, because patient safety and outcomes will depend on the decisions you make during your rotations and while on call. For the topic of Clinical Chemistry, this is that book. This book will be of high value to health profession students and teachers alike." (James M Crawford, Professor and Chair Emeritus, Department of Pathology and Laboratory Medicine, Northwell Health, New Hyde Park, New York, USA) ". Yet it is also remarkably easy to misinterpret and misunderstand the meaning of many results unless one grasps how these tests truly reflect underlying pathophysiology and how they are affected by common clinical scenarios.

This volume is not a simple textbook that passively presents fact after fact to the reader who tries to tie the facts back to the real world. It is a toolkit for firmly embedding the key knowledge about clinical chemistry tests in health care providers so that it becomes a natural part of their approach to diagnosis and treatment. It addresses the common questions that arise in clinical care, based on the rich experience of the authors over decades of consulting as laboratory medicine and clinical chemistry physicians. With didactics based on problem-solving, pithy summaries, and similar tools, it is a knowledge source that one will refer back to time and again." (Brian R. Smith, Professor of Laboratory Medicine, of Biomedical Engineering, of Internal Medicine and Pediatrics, Deputy Dean for Clinical and Translational Research, Yale University, New Haven, Connecticut, USA) "Clinical chemistry is an integral part of clinical pathology because approximately 50% of all clinical pathology testings are performed in clinical chemistry laboratory. Therefore, mastery of this subject is not only essential for clinical pathologists and clinical chemists but also for clinical laboratory scientists. All chapters are well-written, making it the first book which clinical chemistry fellows and pathology residents should buy.

Moreover, each chapter contains clinical cases which are very helpful for learning. I particularly like Appendix C which covers common questions encountered by Pathology residents lacking clinical pathology night call. Also quiz questions in Appendix B are very helpful as a study guide. To summarize, this book is excellent for both teachers and students. All practicing clinical chemists, pathologists, managers and supervisors of clinical laboratory should have easy access to this very valuable resource." (Amitava Dasgupta, Professor of Pathology and Laboratory Medicine, Vice Chair for Clinical Pathology, University of Kansas Center, Kansas, USA) ". The book is the product of over 40 years of teaching this subject by the authors to medical and pharmacy students at the University of California, San Diego. Overall, this is an excellent book that is intended for teaching medical students and those in related fields, and for residents and other trainees in laboratory medicine.

The focus is on the connection between the principles and theory of clinical chemistry and their clinical applications. For an instructor who is looking for a book to serve as a broad foundation for a course in clinical chemistry, this would be an excellent choice. It includes available PowerPoint slides, practical laboratory guidance, and quizzes. The inclusion of quizzes with answers makes it suitable for personal study. The level is appropriate for first-time learners such as medical students and there are ample references to the primary literature for readers who wish to pursue topics in greater depth." (Anthony Killeen, Ellis S. Benson Professor and Vice-Chair for Clinical Affairs, Dept. of Laboratory Medicine & Pathology, University of Minnesota, Minnesota, USA).