This important new bock provides the fundamental understanding of the peptide and protein drug delivery systems, with a special focus on their nanotechnology applications. Addressing an increasing interest in peptide and protein drug delivery systems in both academic and industrial circles worldwide, this book fills the need for a comprehensive review and assessment of conventional and nonconventional routes of administration. The book provides fundamental and comprehensive information regarding the synthesis, stability, degradation, and physicochemical aspects of proteins and peptides. It also addresses barriers to peptide and protein delivery and examines formulation and delivery strategies. The book goes or to discuss pharmacokinetic considerations; methods of preparation, design and synthesis of peptides; structure-function relationships; peptide-polymer conjugates; peptide-encapsulating nanoparticies: biomedical applications of peptide-polymer conjugates; and nonpeptide targeting. This book addresses the growing interest in the area of peptide and protein drug delivery and provides a framework for the pharmaceutical or biotechnological scientist to formulate a strategy to deliver peptide and protein drugs to their sites of action. This book is the first book to discuss these three key features that are current in demand simultaneously: peptides, nanoparticles, and drug delivery. The book introduces some novel classes of peptides and classifies according to their DD applications.
According to the author's survey, more than 30% of highly reputed biomedical science articles published today explore peptide-mediated nanotechnology. This is the first book to provide a clear overview and will be of interest and value to students, researchers, biologists, pharmacists, chemists, chemical engineers, and particularly to protein biochemists, chemical biologists, molecular biologists, microbiologists, geneticists, bioinformaticians, biotechnologist, NDDS, and other professionals who are interested in associated areas. Book jacket.