This textbook builds on the success its two previous editions, offering alternative strategies for discovering new antibiotics. It discusses how the various types of antibiotics and related drugs work to cure infections, and explores the very serious matter of how bacteria are becoming resistant to these antibiotics. It also covers the global action plan on antimicrobial resistance from the World Health Organization and discusses several Antibiotic Stewardship Programs adopted by agencies at local levels. Designed for a one-semester course at either the graduate or advanced undergraduate level, this self-contained textbook provides all the necessary background in biochemistry and is written in accessible language. It discusses the latest developments in the field of antibiotics, emphasizing experimental procedures and interpretation of results, and frequently cites original research to support learning. To help both students and instructors, the book includes approximately 500 multiple-choice questions on antibiotcs. Test your knowledge with questions and answers about this textbook with Springer Nature Flashcards.