Michael Blake began writing while serving in the U.S. Air Force during the Vietnam War when he was stationed at Walker Air Force Base, where he wrote for the base newspaper. He studied journalism at the University of New Mexico, and later studied at a film school in Berkeley, California. He also attended Eastern New Mexico University in Portales. In the late 1970s, he moved to Los Angeles; during the 1980s, only one of his screenplays was produced, called Stacy's Knights. The movie starred Kevin Costner, who later encouraged him to continue to write, and introduced him to key figures in the Hollywood Industry. Dances with Wolves was the result; Kevin Costner then asked him to write a screenplay for the film based on the novel, for which he won an Academy Award.

He died in 2015.