John Goodfellow practised for 35 years as a Consultant Surgeon at the Nuffield Orthopaedic Centre, Oxford, and for much of that time was engaged in studies of the mechanics and kinematics of the knee and knee prostheses. In 1974 he, with John O'Connor, introduced mobile bearing arthroplasty into orthopaedic practice and since the 1980s he has been a proponent of unicompartmental arthroplasty as a better alternative than total knee replacement for many patients with osteoarthritis. John O'Connor was University Lecturer and later Professor of Engineering Science in the University of Oxford, a tutorial Fellow in Engineering Science at St Peter's College, and Research Director at the Oxford Orthopaedic Engineering Centre. As co-inventor of the Oxford Knee he has for many years studied the biomechanics of the human joint before and after knee arthroplasty. Christopher Dodd studied medicine at Sheffield University. Following surgical training at Cambridge and Oxford he became Consultant Orthopaedic Surgeon at the Nuffield Orthopaedic Centre and specialises in surgery of the knee. David Murray initially read engineering at the University of Cambridge but then changed to medicine. Following training in both Cambridge and Oxford, he was appointed a Consultant Orthopaedic Surgeon at the Nuffield Orthopaedic Centre in 1993, and subsequently as a Professor in the University of Oxford.

He has specialised in surgery of the hip and knee, and has a particular interest in unicompartmental knee replacement.