Section 1.- Background Principles and Technical Development.- 1 - Introduction and the Nature of Radiosurgery.- 2 - Principles of Stereotaxy.- 3 - Ionising Radiation and its Effects on Living Tissue.- 4 - Biological Effects of Ionising Radiation.- 5 - Ionising Radiation and Clinical Practic.- 6 - Gamma Knife Development from 1967 to 2010.

- 7. Radiophysics, Radiobiology and the Gamma Knife.- 8 - Preparation for Treatment Planning.- 9 - Dose plan Indices.- Section 2.- The Patient's Experience.- 10 - Gamma Knife surgery and computer networks.- 11 - Aims of Gamma Knife Surgery.

- 12 - Principles of Information and Follow Up.- Section 3.- The Gamma Knife and Specific Diseases.- Tumours.- 13 - Vestibular Schwannomas.- 14 - Meningiomas.- 15 - Gamma Knife for Cerebral Metastases.- 16 - Intraparenchymal Intrinsic Brain Tumours.

- 17 - Tumours of the Pituitary Region.- 18 - Less Common Skull Base Tumours.-.- Section 3.- The Gamma Knife and Specific Diseases.- Vascular Diseases.- 19 - Gamma Knife for Cerebral Vascular Anomalies.- Section 3.

- The Gamma Knife and Specific Diseases.- Functional Indications.- 20 - Trigeminal Neuralgia.- 21 - Diverse Functional Indications.- Section 3.- The Gamma Knife and Specific Diseases.- Less Common Indications.- 22 - Rare tumours and other lesions.

- 23 - Orbital Indications.- Section 4.- Conclusions.- 24 - Conclusion and possible Future Trends.- Appendix - Simple Unassisted Frame Application.- Index.