Proactive obsolescence management helps nuclear power plants anticipate challenges, implement solutions, and safeguard operation and safety. A proactive obsolescence management programme enables operating nuclear power plants to anticipate obsolescence challenges and develop effective solutions without compromising plant operation or safety. This publication presents a collection of practices and experiences related to establishing and implementing such programmes. It highlights lessons learned during implementation and examines the role of regulatory bodies in obsolescence oversight. It also provides examples of successful, real world obsolescence solutions.