Teaching is a profession of passion, but it also demands an extraordinary amount of time and energy. The time it takes to plan lessons, grade assignments and tests, and differentiate instruction all add up, and teachers often work far beyond contracted hours just to keep up. AI will never be a replacement for outstanding teaching. Still, it can serve as a handy assistant to help you streamline tasks, increase efficiency, and create more space for what matters most: engaging with students and fostering meaningful learning experiences. This guide explores how AI can support teachers in lesson and unit planning, making substitute plans, grading, and differentiation. You will learn how AI can help lighten your workload while maintaining high-quality instruction. If you have questions about the basics, like what AI is, how it works, or what to do about protecting student data, please refer to the first guide in this three-part series of laminated guides on AI entitled AI in Education 101: A Teacher's Guide. If you understand the basics and are ready to learn more about the practicalities of implementing AI as a teacher, this is the guide for you!.