Is the perfect murder the one you can't forget or the one you can't remember? Dr. Jennifer White, a brilliant former surgeon in the early grips of Alzheimer's, is suspected of murdering her best friend, Amanda. Amanda's body was found brutally disfigured -- with four of her fingers cut off in a precise, surgical manner. As the police pursue their investigation and Jennifer searches her own mind for fractured clues to Amanda's death, a portrait emerges of a complex relationship between two uncompromising, unsentimental women, lifelong friends who were at times each other's most formidable adversaries.