Responsible Blockchain provides a comprehensive analysis of the challenges and controversies associated with blockchain technology. It identifies technical challenges such as scalability, security, privacy, and interoperability, as well as business and adoption challenges, and the social, economic, ethical, and environmental controversies present in current blockchain systems. The authors argue that responsible blockchain development is key to overcoming these challenges and achieving mass adoption. This monograph defines Responsible Blockchain and introduces the STEADI principles (sustainable, transparent, ethical, adaptive, decentralized, and inclusive) for responsible blockchain development. Additionally, it presents the Actor-Network Theory-based Responsible Development Methodology (ANT-RDM) for blockchains, which includes the steps of problematization, interessement, enrollment, and mobilization.