AI has had notable successes in many scientific and engineering fields. Healthcare and biomedical research are no exceptions, where it is being used to assess physiological measurements, medical images, improving outcome predictions and individualizing therapy. AI is poised to revolutionise areas of precision medicine, particularly with the rise of wearable sensors and -omic technologies. Blockchain in healthcare is less well advanced, but it has the potential to also be transformative. Its ability to keep an incorruptible, decentralized and transparent log of all data makes it a technology ripe for increasing the security, privacy, and interoperability of health data that can protect the sensitivity of medical data. This book reviews the technologies and benefits offered by AI and blockchain in particular, and the integration of both in modern biomedical research.