Introduction: Progress of Process Biotechnology Knowledge Collation and Expansion Bridging the Gap: Biosciences Engineering and Technology Global Impacts and Scenario Forecasting References Engineering Biology of Cells and Molecules they Synthesize: Cell Biology Events Structural Engineering of DNA in Advancing Bioprocess Engineering Biomolecular Design Engineering Tools: Properties and Forefront Applications References Medium Engineering for Cell Cultivation and Bioreactions: Introduction Basic Concept in Medium Design Procedure Design Procedure Basics of Material Balance Growth Limiting Nutrient in the Designed Medium Engineered Medium in Cell Growth and Product Formation Metabolic Engineering Bioorganic Reaction Medium Engineering Novel Media References Contamination Free Fluids for Process Biotecnology: Introduction Contamination Free Air Supply Few Non-conventional Air Borne Particle Removal Methods Contamination Free Medium by Sterilization References Concerns of Aeration and Mixing/Agitation in Bioprocessing: Introduction Oxygen Pathways in Cell Cultivations Volumetric Oxygen Transfer Coefficient (KL a) Oxygen Transfer Mechanism and Parameters Resistances to Gas-Liquid Interface and Bulk Mixing Recent Concept in Oxygen Transfer Pathway Mixing/Agitation in Biofluids Development in Physical Concepts in Liquid Phase Oxygen Transfer Coefficient (KL1) Advances in Oxygen Absorption Mechanism and Influencial Factors Absorption Models Measurements of Dissolved Oxygen (DO), KL a, and Active Oxygen Species Gaseous Oxygen Measurement Assessment of KLa Estimation of Reactive Oxygen Species Conventional and Novel Bioreactors for Cell Cultures Microbial Cell Culture Bioreactos Mammalian Cell Culture Bioreactors Importance of K.L a in Cell Culture Process Scale up Acknowledgement References New Bioprocessing: Aspects and Strategies: Archaebacterial Bioprocessing: Problems and Developments Bioprocessing by Cell Synchronization Recent Advances of Yeast Bioprocessing Multiinteracting Microbial Bioprocessing: Theory, Benefits and Problems Strategies of Cycling and Profiling of Variables in Bioprocessing References Bioreactors and Biosensors: Introduction Bioreactors in Bioprocessing of Biocell Enzyme Bioreactors Biosensors in Bioprocessing References Bioprocessing Scale up: Concerns and Criteria: Introduction Scale up Concerns of Microbial, Mammalian and Plant Cell Processes Scale up Criteria Selection of Scale up Criteria Scale up Genetically Engineered Cell Culture Fermentation References Bioproducts: Modern Estimation and Bioassay : Introduction Online MS Instrumental Analysis Light Scattering Instrumental Analysis Chromatography Instrumental Analysis Flow Injection Instrumental Analysis (FIIA) PCR Instrumental Analysis Few Bioassay Procedures References Bioproducts Recovery : Conventional and Newer Methods : Introduction Conventional Recovery Methods Newer Methods References Treatment Biotechnology of Liquid Wastes and Water: Introduction General Concerns and Principles Treatment Biotechnoogy for Waste Waters Potable Water Treatment Biotechnology Treatment Biotechnology of Genetically Engineered Cell Processing Efflucnts References Control of Undesirable Microorganisms in Biosystems: Introduction Methods of Controlling Undesirable Microoganisms Disinfectant Decay and Bacterial Inactivation Kinetics References Cellulose Processing Relevance to Process Biotechnology: Introduction Cellulase: The Complex Resource Conversion Agent RQ and CQ in T reesei Approaches of Cellulosic Bioprocessing and Co-product Utility Further Scope with Lignocellulose Processing Research Cocktail Enzyme Use in Polysaccharide Systems References Bioprocessing: Using Cells Under Stresses : Introduction Stress Protein Sources and Family Types Nomenclature of Stress Proteins Physiological Stress Inducers and Cross Interactive Stresses SPs Functional Features Molecular Biology of Cell Processing Under Stress Kinetics and Dynamics of Stress Proteins Formation Molecular and Cell Biology (MCB) Techniques in Stress Proteins Analysis Upstream Bioprocessing and Downstream Separation of SPs Future Prospects of SPs Conclusions Acknowledgement References Bioprocess Plant Design Calculations: Penicillin Production System: Introduction Defining the Design Problem Fermenter Design Calculation Items Downstream Process for Recovery by Filtration Downstream Processing for Extraction References Bioprocessing Practice Tutorials : Introduction Microbial Pure Culture Bioprocessing Mixed Microbial Cell Cultures Mammalian Cell Culture System Plant Cell Culture Bioproduct Recovery Additional Practice Tutorials Miscellaneous Multichoice Questions References Substrates for Industrial Process Biotechnology and Their Refining : Introduction Substrates/Resources References Index.