This book demonstrates that innovative ideas are systematically constructed in the creative space spanned by the dimensions of systems thinking and knowledge management. Readers will be introduced to this proposition in the final chapter, after learning about the key innovation theories, design thinking, systems thinking, and idea creation methods in systems science and knowledge science. The content provided throughout the book supports knowledge creation in various fields, the management of research and business projects, and the creation of promotion stories for products and services. Practitioners who are seeking to create innovative ideas can systematically learn the minimum theories and methods required, while graduate students will be equipped to link their research to innovation by learning the essence of systems science and knowledge science and considering selected issues. Lastly, the book includes suggestions for future research directions in knowledge science.