Preface xv 1 Nanocarriers for Diagnosis and Treatment of Oncology 1 Mohammad Javad Javid-Naderi, Fatemeh Akbarzadeh-Ebrahimi, Dora Iliana Medina and Abbas Rahdar 1.1 Introduction 2 1.2 Types of Nanocarriers 3 1.3 Nanocarriers in Cancer Diagnosis 8 1.4 Nanocarriers in Cancer Treatment 14 2 Artificial Intelligence in Modern Healthcare 35 Hamidreza Hosseini, Abbas Rahdar, Abolfazl Tabatabaei, Sadanand Pandey and Maryam Shirzad 2.1 Introduction to AI 36 2.2 Features of Medical Images 50 2.3 Leading CAD Systems 53 2.
4 Recent Developments in the Field of DL 56 2.5 Clinical Requirements and Obstacles 58 2.6 Applications in the Area of Medicine and Healthcare 59 2.7 CAD Pulmonary Artery Occlusion 60 2.8 CAD (Computer-Aided Diagnosis) Compatible with Lung Nodules 61 3 Foundation of AI-Enhanced Nanocarriers 121 Pejman Zarbanooei, Sanaz Aliakbarzadeh, Abbas Rahdar and Maryam Shirzad 3.1 Introduction 122 3.2 Introduction to Intelligent Nanocarriers: Bridging AI and Nanomedicine 124 3.3 Fundamentals of Artificial Intelligence in Oncology: A Primer 129 3.
4 Nanocarriers in Cancer Therapy: An Overview of Traditional vs. AI-Enhanced Approaches 143 3.5 Conclusion and Future Prospects 145 4 Design and Development of AI-Based Nanocarriers 157 Ashkan Hajjafari, Narges Lotfalizadeh, Mansour Bayat, Abbas Rahdar, Maryam Shirzad and Guettari Moez 4.1 Introduction 158 4.2 Machine Learning Algorithms in Nanocarrier Design: Optimization and Innovation 161 4.3 AI-Driven Predictive Modeling for Nanocarrier Efficacy and Safety 167 4.4 Smart Materials (SMs) for Intelligent Nanocarriers: Integration of AI and Nanotechnology 174 4.5 Future and Challenges 181 5 Artificial Intelligence (AI) in Cancer Diagnosis and Targeting 195 Fatemeh Momtaz, Elham Momtaz, Mahdieh Momtaz, M.
Ali Aboudzadeh and Abbas Rahdar 5.1 Introduction 196 5.2 AI-Powered Imaging Techniques for Early Cancer Detection 197 5.3 Precision Targeting: AI''s Role in NanocarrierBased Drug Delivery Systems 205 5.4 TME and AI: Enhancing Targeted Delivery of Nanocarriers 212 5.5 Challenges and Opportunities 218 5.6 Conclusion 219 6 Artificial Intelligence (AI)-Based Nanocarriers in Cancer Therapy 233 Mahdieh Momtaz, Elham Momtaz, Fatemeh Momtaz, Zeinab Moafian, Suresh Ghotekar and Abbas Rahdar 6.1 Introduction 234 6.
2 AI for Predicting Nanocarrier Performance 235 6.3 AI-Powered High-Throughput Screening for Nanocarrier Formulation 245 6.4 Role of AI in Stimuli-Responsive Nanocarriers 251 6.5 Challenges and Opportunities 265 6.6 Conclusion 265 7 Artificial Intelligence (AI)-Enabled Nanocarriers in Cancer Diagnosis 283 Zakieh Sadat Hoseini, Amir Mohammad Najafi, Fatemeh Nouri Rouzbahani, Renato Nery Soriano and Abbas Rahdar 7.1 Introduction 284 7.2 Advancements in Nanotechnology and AI: Transforming Diagnostic Imaging 286 7.3 Nanocarrier-Assisted AI for Liquid Biopsy: Enhancing Circulating Tumor Cell Detection and Biomarker Extraction 294 7.
4 Nanoparticle-Integrated, AI-Enhanced Biosensors for Real-Time Cancer Diagnostics 300 7.5 Future Prospects of AI-Driven Nanocarriers in Cancer Detection 306 7.6 Conclusion 307 8 AI-Based Nanocarriers in Gene Therapy and Immunotherapy 319 Heshmat Razlansari, Mahtab Razlansari, Masoud Kahrizi, Mohsen Kahrizi and Abbas Rahdar 8.1 Introduction 320 9 Clinical Applications and Case Studies 357 Roghaieh Holghoomi, Abbas Rahdar and Renato Nery Soriano 9.1 Introduction 358 9.2 Clinical Applications of Artificial Intelligence-Enhanced Nanocarriers: Current Progress and Future Prospects 362 9.3 Case Studies: Artificial Intelligence-Driven Nanocarrier Systems in Personalized Cancer Therapy 372 9.4 Overcoming Challenges: Artificial Intelligence and Nanocarrier Synergy in Complex Oncological Cases 374 9.
5 Conclusion 375 10 AI-Guided Radiotherapy and Nanocarrier Synergy to Treat Cancers 381 Mehrab Pourmadadi, Zahra Omrani, Abbas Rahdar, Elvis Fosso-Kankeu and Sadanand Pandey 10.1 Introduction 382 10.2 Artificial Intelligence-Based Radiotherapy to Treat Cancers 384 10.3 AI-Guided Radiotherapy and Nanocarrier Synergy to Treat Cancers: "Combining Radiotherapy with AI-Enhanced Nanocarriers to Improve Therapeutic Outcomes" 395 10.4 Future Perspective 401 10.5 Conclusion 402 11 Integrating Artificial Intelligence and Quantum Computing with Omics Data for Cancer Therapy and Diagnosis 413 Ali Bakhshi, Mahya Bakhshi, Mojtaba Hosseine, Hossein Hasannezhad, Abbas Rahdar, Elvis Fosso-Kankeu and Sadanand Pandey 11.1 Introduction 417 11.2 What is Omics? 422 11.
3 Omics Data 430 11.4 AI-Driven Multi-Omics Integration for Cancer Diagnosis 444 11.5 AI-Driven Multi-Omics Integration in Cancer Therapy 453 11.6 Integration of Artificial Intelligence and Omics Technologies for Precision Oncology 478 11.7 Quantum Artificial Intelligence in Oncology 482 11.8 Challenges and Opportunities 491 11.9 Future Perspective 494 12 Ethical, Regulatory, and Future Perspectives 525 Sanaz Aliakbarzadeh, Pejman Zarbanooei, Majid Abdouss, Abbas Rahdar and Luiz Fernando Romanholo Ferreira 12.1 Introduction 526 12.
2 Ethical Issues with AI and Nanocarrier Applications in Oncology 529\ 12.3 Regulatory Challenges and Pathways for AI-Enhanced Nanocarrier Therapies 543 12.4 The Future of Intelligent Nanocarriers: Innovations, Challenges, and Opportunities 548 12.5 Conclusion and Future Perspectives 561 References 563 Index 571.