1. Introduction to Genetics 1.1 Genetics Is Important to Individuals, to Society, and to the Study of Biology 1.2 Humans Have Been Using Genetics for Thousands of Years 1.3 A Few Fundamental Concepts Are Important for the Start of Our Journey into Genetics New Chapter Opening Story: Albinism in the Hopis Expanded section on model genetic organisms, using the golden mutation in zebrafish as an example 2. Chromosomes and Cellular Reproduction 2.1 Prokaryotic and Eukaryotic Cells Differ in a Number of Genetic Characteristics 2.2 Cell Reproduction Requires the Copying of the Genetic Material, Separation of the Copies, and Cell Division 2.
3 Sexual Reproduction Produces Genetic Variation Through the Process of Meiosis Revised discussion of the cell cycle Updated coverage of the separation of sister chromatids and homologous chromosomes, including a discussion of shogoshin 3. Basic Principles of Heredity 3.1 Gregor Mendel Discovered the Basic Principles of Heredity 3.2 Monohybrid Crosses Reveal the Principle of Segregation and the Concept of Dominance 3.3 Dihybrid Crosses Reveal the Principle of Independent Assortment 3.4 Observed Ratios of Progeny May Deviate from Expected Ratios by Chance New Chapter Opening Story: The Genetics of Red Hair Five new Data Analysis Problems featuring real data from scientific papers 4. Sex Determination and Sex-Linked Characteristics 4.1 Sex Is Determined by a Number of Different Mechanisms 4.
2 Sex-Linked Characteristics Are Determined by Genes on the Sex Chromosomes Model Genetic Organism: The Fruit Fly Drosophila melanogaster Revised discussion of nondisjunction and the Chromosome Theory of Inheritance New in-text Worked Problem Updated discussion of X-inactivation Two new Data Analysis problems featuring real data from scientific papers 5. Extensions and Modifications of Basic Principles 5.1 Dominance Is Interaction Between Genes at the Same Locus 5.2 Penetrance and Expressivity Describe How Genes Are Expressed As Phenotype 5.3 Lethal Alleles May Alter Phenotypic Ratios 5.4 Multiple Alleles at a Locus Create a Greater Variety of Genotypes and Phenotypes Than Do Two Alleles 5.5 Gene Interaction Occurs When Genes at Multiple Loci Determine a Single Phenotype 5.6 Sex Influences the Inheritance and Expression of Genes in a Variety of Ways 5.
7 Anticipation Is the Stronger or Earlier Expression of Traits in Succeeding Generations 5.8 The Expression of a Genotype May Be Influenced by Environmental Effects New Chapter Opening Story: Cuénot's Odd Yellow Mice New extended example to introduce the concept of epistatsis New example to demonstrate recessive epistasis: Bombay phenotype New in-text Worked Problem Five new Data Analysis Problems featuring real data from scientific papers 6. Pedigree Analysis, Applications, and Genetic Testing 6.1 The Study of Genetics in Humans Is Constrained by Special Features of Human Biology and Culture 6.2 Geneticists Often Use Pedigrees to Study the Inheritance of Characteristics in Humans 6.3 Analysis of Pedigrees Requires Recognizing Patterns Associated with Different Modes of Inheritance 6.3 The Study of Twins Can Be Used to Assess the Importance of Genes and Environment on Variation in a Trait 6.4 Adoption Studies Are Another Technique for Examining the Effects of Genes and Environment on Variation in Traits 6.
5 Genetic Counseling Provides Information to Those Concerned about Genetic Diseases and Traits 6.6 Genetic Testing Provides Information about the Potential for Inheriting or Developing a Genetic Conditio.