God: The Play is a story about an inquisitive college student named Jude. He is a scholar and contender for valedictorian of his graduating class. He has completed an academically demanding program with a double major in English and drama, which requires a thesis to graduate. Jude's professor gave him the thesis topic: Does God exist, or not? He decides to write and perform a play to fulfill this requirement, and he uses his fellow drama students as the actors. God: The Play begins with a series of opinionated characters presenting unconventional insights into the existence of God. It is the intent of these composite characters to provide new perceptions on old beliefs, including unique ideas about God. These characters do not intend to leave the audience resting comfortably in their current beliefs as an atheist, a member of a religious sect, or a scientist. In their dialogue, the characters examine human tolerance for believing in irrational, intangible ideas, even if one's belief is non-belief.

The characters use "dialectic rhetoric" to "inquire, argue and persuade" in seeking the truth about God's existence through "closed fist" and "open hand" discussions as described by philosophers such as Zeno the stoic, Hegel, Aristotle, Socrates, Plato and Cicero.