This book gives an account of the new possibilities and difficulties of long-term living with HIV and antiretroviral treatment. It takes an international perspective, looking at commonalities and differences across high and middle-income countries. The book draws on narrative data collected over a long period in the UK and South Africa. Analysing these stories, it argues that the HIV pandemic still presents highly particular issues that we need to address. The book suggests that HIV's present 'naturalized' incorporation into policy and everyday life is incomplete and difficult. It describes the medicalization, normalization and marketization processes that characterize current political, policy and popular approaches to HIV, and argues that these processes often fail or are resisted by people living with HIV. Finally, it describes people living with HIV's own new narrative strategies for constructing, protecting and extending their HIV citizenship.