The second edition of Great American Diseases continues the important coverage of significant disease epidemics that have affected North America, ranging from the arrival of smallpox with the first Europeans to updated information on the COVID-19 pandemic, it includes an introductory chapter on the basic science behind disease, as well as a new chapter on the history of vaccination in the Americas. Subsequent chapters discuss various diseases, their pathogens, and their social ramifications through the history of North America; and the book concludes with a new chapter on notable animal disease outbreaks. This easy-to-read volume provides an interesting and engaging introduction to microbiology, immunology, and epidemiology with up-to-date and contemporary outbreak examples and is a valuable resource for all biomedical students. Key Features, Focuses on the major infectious and parasitic diseases of North America, Includes new chapters on the history of vaccination and significant animal diseases, Provides historical and scientific information in an easy-to-digest volume, Covers the basic science of bacteriology, virology, immunology, and epidemiology.