What If Healthcare Finally Worked the Way People Needed It To? By 2035, healthcare as we know it will be unrecognizable. The next transformation will not be led by hospitals, insurers, or government policy-but by AI, home diagnostics, patient-owned data, continuous monitoring, retail health, and a new generation of self-care platforms operating outside the traditional clinical model. In Multi-Trillion Dollar U.S. Healthcare to 2035: Gold Rush II, Edmund L. Valentine examines how the coming decade will reshape the $4.7 trillion U.S.

healthcare system. Drawing on decades of industry analysis, he introduces and defines the Self-Care Operating System¿-the next foundational layer of healthcare-designed to enable continuous, preventive, and predictive care at national scale. Valentine explains: ¿ Why the legacy healthcare model is collapsing under economic, demographic, and workforce pressure ¿ How AI becomes the new clinical operating layer-governing detection, escalation, and care coordination ¿ Why employers, payers, and retailers emerge as the new centers of healthcare power ¿ How home diagnostics and distributed care displace episodic, facility-based medicine ¿ Why continuous self-care is the only scalable response to chronic disease ¿ Who wins, who loses, and how every stakeholder must adapt Written for clinicians, executives, investors, entrepreneurs, policymakers, and citizens navigating an uncertain system, this book offers a clear, unsentimental, and ultimately optimistic framework for understanding what comes next. This is not a prediction. It is the operating logic of the next healthcare economy.