Volume 1:art 1: Immunological Basis of the Allergic Response:Short History of Allergological Diseases and Concepts;oncepts of Allergy and Hypersensitivity;and B Lymphocytes and the Development of Allergic Reactions;mmunoglobulin Structure, Synthesis and Genetics;gE and IgE Receptors;egulation of IgE Synthesis;ntigen Processing and Presentation;mmunological Tolerance and T-Cell Anergy;art 2: Inflammatory Cells and Mediators:uman Mast Cells and Basophils;osinophils and the Allergic Inflammatory Response;he Neutrophil;latelets;acrophages and Dendritic Cells in Allergic Reactions;eucocyte Adhesion in Allergic Inflammation;irway Epithelium in Asthma;ndothelial Cells in Allergy;ibroblasts and Bronchial Asthma;omplement and Antigen-Antibody Complexes;ntrinsic Coagulation/Bradykinin-Forming Cascade;ytokines (Interleukins);ole of IL-5, IL-3 and GM-CSF in the Pathophysiology of Asthma and Allergy;hemokines;ipid Mediators - Leukotrienes, Prostanoids and Platelet-Activating Fact∨art 3: Pharmacology:istamine and Antihistamines;ascular Permeability and Plasma Exudation;europeptides;he Autonomic Nervous System in Asthma and Rhinitis;europharmacology;ndothelin and Nitric Oxide;heophylline and Isoenzyme-Selective Phosphodiesterase Inhibitors;drenergic Agonists and Antagonistis;edocromil Sodium and Sodium Cromoglycate: Pharmacology and Putative Modes of Action;holinergic Antagonists;otassium Channel Openers as Anti-Asthma Drugs;lucocorticosteroids;mmunosuppressants (Drugs and Monoclonal Antibodies);art 4: Physiology:hysiological Aspects of Airway, Pulmonary and Respiratory Muscle Function in Asthma;ronchial Hyperresponsiveness;xercise-Induced Asthma;ucus and Mucociliary Clearance;ew Approaches in Aerosol Drug Delivery for the Treatment of Asthma;irway Smooth Musc≤art 5: Cellular and Molecular Techniques in the Study of Allergic Disease:-Cell Cloning;n Situ Hybridization;mmunocytochemistry;olymerase Chain Reaction;olume 2:art 6: Allergens:iochemistry of Allergens;olecular Cloning of Allergens;llergen Extracts and Standardization;rass, Tree and Weed Pollens;ungi and Actinomycetes as Allergens;ust Mites and Asthma;nimal Allergens;llergens in the Workplace;llergens from Stinging Insects;ockroach Allergens and their Role in Asthma;hronomidae;ood Allergens;atex Allergy;art 7: Diagnostic Methods and the Assessment of Allergic Diseases:rinciples and Interpretation of Laboratory Tests for Allergy;kin Tests;uantification of IgE both as Total Immunoglobulin and as Allergen-Specific Antibody;art 8: Major Animal Models of Asthma and Hyperresponsiveness:rimate Models of Allergic Asthma;heep Models of Allergic Broncoconstriction;urine Models of Allergy, Asthma and Hyperresponsiveness;he Allergic Response in Rats;he Rabbit as an Animal Model of Allergy, Asthma and Airway Hyperresponsiveness;he Sensitized Guinea Pig as a Model of Allergic Asthma;anine Models of Asthma and Hyperresponsiveness;art 9: Human Models of Allergic Inflammation (Late-Phase Reactions):uman Late Asthmatic Responses;ate-Phase Skin Reactions;ate-Phase Reactions in the Nose;art 10: General Principles of the Allergic Response in Humans:llergy and Helminthic Parasites: Are Atopics Protected Against Infection'amilial Inheritance of Asthma and Allergy;enetics of Atopy;enetics of Allergy and Asthma;pidemiology of Atopy and Atopic Disease;art 11: Allergen Injection Immunotherapy:echanisms;ndications for Specific Immunotherapy;ractical Immunotherapy;art 12: The Practice of Allergology:llergology as a Medical Specialty or Sub-Specialty;rinciples and Practice of Diagnostic and Treatment of Allergic Disease;art 13: Seasonal and Perennial Rhinitis:he Classification and Diagnosis of Rhinitis;tructure and Function of the Upper Airways;easonal and Perennial Allergic Rhinitis;reatment and Management;art 14: Asthma:efinition, Clinical Features, Investigations and Differential Diagnosis of Asthma;ost-Mortem Pathology in Asthma;etiology and Pathogenesis of Asthma;he T-Cell Hypothesis of Chroniic Asthma;ir.