This book gives information about the newest methods for limb salvage in musculoskeletal oncology. The contributions describe concepts of chemotherapy, immunotherapy, radiation therapy, hyperthermia, and biomechanical and biomaterial design for the fabrication of tumor prosthesis. Functional results in terms of limb salvage are evaluated by an internationally accepted rating system. Various modern approaches to limb salvage for malignant musculoskeletal conditions are given.