In this issue of Gastrointestinal Endoscopy Clinics of North America , guest editor Dr. Amy E. Hosmer brings her considerable expertise to the topic of Endoscopic Closure Techniques . These techniques provide minimally invasive solutions for managing gastrointestinal perforations, leaks, and fistulas, and offer a safer and more efficient alternative to traditional surgical interventions, reducing patient morbidity and recovery time. Recent advancements in endoscopic devices and materials have expanded the therapeutic capabilities of GI endoscopists, allowing for precise and reliable closure of even complex lesions. This issue provides current, state-of-the-art clinical reviews on endoscopic closure techniques to facilitate better patient outcomes. Contains 11 relevant, practice-oriented topics including advancements in endoscopic closure: the current armamentarium of available devices; recognition of gastrointestinal perforations: diagnosis and therapy; approach to the patient with a gastrointestinal perforation; endoscopic stenting in the management of gastrointestinal perforations; comparison and cost effectiveness of endoscopic closure techniques; and more Provides in-depth clinical reviews on endoscopic closure techniques , offering actionable insights for clinical practice Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.