Adult cerebral infections are a common neurosurgical emergency presentation in the UK. This Element provides a comprehensive guide for clinicians, detailing the epidemiology, aetiology, and risk factors associated with the various types of cerebral infections including cerebral abscess, subdural empyema, epidural abscess and cranial fungal and parasitic infections. The clinical presentation, diagnostic methods, and treatment options, including surgical and antibiotic management, are discussed. Emphasis is placed on the importance of early diagnosis and tailored treatment plans. Flow diagrams summarizing the management of cerebral infections are also provided in this Element.