Overview on sporadic and NF-related tumors.- Natural history and clinical evolution of PNST in neurofibromatosi.- Advancement in genetic and molecular landscapes.- Multi-omic analyses for biomarker discovery and characterization of PNST.- Preclinical NF1-PNST models and potential drug resistance mechanism.- MRI in the diagnosis of PNST: state-of-the-art and recent advancements.- Developing the role of molecular imaging PET in PNST.- A clinical summary of PNST in adults.

- Clinical assessment of tumor predisposition syndromes - related nerve sheath tumors in children.- IOUS and CEUS in PNS tumor.- Neurophysiological evaluation and intraoperative neurophysiology monitoring in peripheral nervous system tumor.- Surgical management of peripheral nerve sheath tumors.- Surgical Management of Pediatric PNS.- Fluorescent-guided surgery of PNST.- Esoscope in PNS tumors surgery.- Preserving nerve function and reconstruction in MPNS tumors.

- New oral chemotherapy and MEK inhibitor (and other treatments for benign PNST).- Systemic treatment in malignant peripheral nerve sheath tumors: current practice and future possibilities.- Proton and carbon ion therapy for MPNST.- Radiomics and machine learning in PNST.