Chiral Recognition and Separation Mechanisms
Introduction. Symmetry. Separation of Enantiomers through the Formation of Diastereomers. Non-chromatographic Methods for the Determination of Enantiomeric Excess. Mechanism of Chromatographic Chiral Discrimination & Thermodynamics of Chromatographic Chiral Discrimination. Chiral Separation with Taylor Made Polymers. Chiral Separation through Ligand Exchange. Chiral Separation through H-bonds.
Chiral Separation through Charge Transfer. Chiral Separation through Inclusion Compounds. Protein Phases and Antibiotic Phases. Polysaccharide Phases. Separation of Enantiomers with Chiral Mobile Phases. Strategies for Method Development for Chiral Separation. Conclusion/Summary and Future Possibilities.