In this issue of Critical Care Clinics , guest editors Drs. Sameer S. Kadri-Rodriguez and Christina Yek bring their considerable expertise to the topic of Infectious Diseases in the Intensive Care Unit . Top experts cover key issues such as management of meningitis and encephalitis; the global ICU: malaria, tuberculosis, HIV, and more; optimal pathways for source control in the ICU; lower respiratory tract infections: precision diagnostics; and much more. Contains 13 relevant, practice-oriented topics including recognition and management of infectious biothreats and emerging pathogens; the respiratory tripledemic: management of influenza, COVID-19, and RSV in the adult ICU; antibiotic considerations in the critically ill: empiric choices and dosing; infection prevention and control for the ICU; and more Provides in-depth clinical reviews on infectious diseases in the intensive care unit , offering actionable insights for clinical practice Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.