List of Contributors xxi About the Editors xxv Preface to Fourth Edition xxvii About the Companion Website xxix 1 General Microbiology 1 Howard F. Jenkinson and Daniel P. Miller 2 The Immune System and Its Functions 33 George Hajishengallis and Jonathan M. Korostoff 3 The Oral Environment 65 Frank A. Scannapieco, Christian P. Ahearn, and Stefan Ruhl 4 Methodologies for Evaluation of Oral Microbiome Composition and Functional Capacity 99 Patricia I. Diaz, Georgios N. Belibasakis, and Anilei Hoare 5 Oral Microbial Ecology 119 Richard J.
Lamont, Howard F. Jenkinson, and Matthew Ramsey 6 Oral Microbial Physiology 143 Jorge Frias-Lopez and Paul G. Egland 7 Genetics and Molecular Microbiology of Oral Bacteria 191 Justin Merritt 8 Applied Molecular Approaches to Oral Microbial Ecology and Community Development 215 Jens Kreth 9 From Bacterial Genetics to Genomics 237 Jonathon L. Baker 10 Structure and Function of Oral Mucosal Tissues 251 Kyulim Lee and Juhi Bagaitkar 11 Immunology of the Oral Cavity 271 Evlambia Hajishengallis and George Hajishengallis 12 Aging, Epigenetics, and Oral Immunity 297 Sinem Esra Sahingur 13 Dental Caries: Etiology and Pathogenesis 321 Livia M.A. Tenuta, Hyun Koo, and Jaime A. Cury 14 Microbial Pathogenesis of Dental Caries 339 José A. Lemos, Hui Wu, and Hyun Koo 15 Microbiology of Periodontal Diseases: General Concepts 359 Georgios N.
Belibasakis and Nagihan Bostanci 16 Virulence Factors of Periodontal Bacteria 371 Richard J. Lamont, Janina P. Lewis, and Jan Potempa 17 Immunopathogenic Mechanisms in Periodontal Disease 403 George Hajishengallis 18 Oral Virology 437 Afsar Naqvi and Joel Schwartz 19 Fungi and Fungal Infections of the Oral Cavity 477 Richard D. Cannon, Guangzhao Guan, and Norman A. Firth 20 Endodontic Infections and Therapeutic Approaches 499 Brenda P.F.A. Gomes, Isabela N.
Rôças, and José F. Siqueira Jr. 21 Systemic Disease and the Oral Microbiota 517 Nagihan Bostanci and Georgios N. Belibasakis 22 Systemic Antibiotics in Dental Practice: Principles, Indications, and Stewardship 537 Zayed Naiera, Feres Magda, Saghi Mehraveh, and Wim Teughels 23 Therapeutic Approaches for Biofilm Control and Host Modulation in Oral Diseases 595 Yuan Liu, George Hajishengallis, Hyun Koo, and Zhi Ren 24 Infection Prevention and Control in Dentistry 627 J. Christopher Fenno and Brandonn K. Perry KEY POINTS 652 FURTHER READING 653 Index 655.