Table of Contents Introduction by Naomi R. Fogel, MD Acute Kidney Injury in a Previously Healthy 15-year-old Patient Secondary Amenorrhea in a 15-year-old Girl An Adolescent with Unusual Behavior Delayed Puberty and Incidental Hypertension in a 14-year-old Girl New-Onset Diabetes in a 17-year-old Girl with Primary Amenorrhea Altered Mental Status in a 5-year-old Girl Vaginal Bleeding in a 3-year-old Severe Intrauterine Growth Restriction and Postnatal Growth Failure in a Term Neonate A 4 year-old Girl with Diabetic Ketoacidosis and Lipemic Blood Abnormal Eye Movements and Hypernatremia in a 4-month-old Girl Short Stature and Brachydactyly in an 8-year-old Girl with Congenital Hypothyroidism Case 1: Clitoromegaly, Oligomenorrhea, and Hirsutism in a 17-year-old Transgender Male Case 2: Worsening Anxiety in an Adolescent: The Role of Anchoring Bias Case 3: Psychiatric Distress, Hypertension, and Weight Gain in an Adolescent Male Acute Odynophagia in an 11-year-old Girl A Rare Diagnosis for Vomiting and Polyuria: The Pituitary, the Adrenal Gland, the Thyroid Failure to Thrive in a 15-month-old with a History of Head Trauma Hirsutism and Menstrual Irregularity in a 16-year-old Girl Recurrent Vomiting in a 6-year-old Boy Left Leg Pain in a 9-year-old Boy.