The 2025-26 Guide to Medications for the Treatment of Diabetes Mellitus is a complete and newly revised reference for every physician, clinician, and educator treating people with diabetes. Compiled and edited by a team of noted pharmacology experts specializing in diabetes care, this guide addresses all aspects of diabetes drug classes including insulins, biguanides, thiazolidinediones, sulfonylureas, glinides, SGLT2 inhibitors, alpha-glucosidase inhibitors, DPP-4 inhibitors, GLP-1 RAs, pramlintide, bile acid sequestrants, and dopamine-2 RAs. Each discussion reflects the latest guidance of the American Diabetes Association's Standards of Care in Diabetes . This guide also features chapters on medication management of comorbidities such as: Neuropathy; Chronic Kidney Disease; Retinopathy; Hypoglycemia; Obesity; Depression.