List of contributors xix Preface xxiii Part I The pathogenic clostridia 1 1 Taxonomic relationships among the clostridia 3 Paul A. Lawson 2 General physiological and virulence properties of the pathogenic clostridia 9 Julian I. Rood 3 Brief description of animal pathogenic clostridia 15 Iman Mehdizadeh Gohari Part II Toxins produced by the pathogenic clostridia 25 4 Toxins of histotoxic clostridia: Clostridium chauvoei, Clostridium septicum, Clostridium novyi, Paraclostridium sordellii, Clostridium histolyticum 27 Michel R. Popoff 5 Toxins of Clostridium perfringens 67 James R. Theoret, Iman Mehdizadeh Gohari, and Bruce A. McClane 6 Toxins of Clostridioides difficile 83 Panagiotis Papatheodorou 7 Clostridium botulinum and Clostridium tetani neurotoxins 95 Michel R. Popoff Part III Clostridial infections of the gastrointestinal system 163 8 Diseases produced by Clostridium perfringens type A in animals 165 Francisco A. Uzal and Mauricio A.
Navarro 9 Infections by Clostridium perfringens type B 175 Francisco A. Uzal and John S. Munday 10 Diseases produced by Clostridium perfringens type C 183 Santiago S. Diab and Horst Posthaus 11 Diseases produced by Clostridium perfringens type D 199 Francisco A. Uzal, Federico Giannitti, John W. Finnie, and Jorge P. García 12 Diseases produced by Clostridium perfringens type E 219 Mauricio A. Navarro and Francisco A.
Uzal 13 Clostridium perfringens type F infections of animals 223 Iman Mehdizadeh Gohari and Bruce A. McClane 14 Diseases produced by Clostridium perfringens type G 231 Kerry K. Cooper and Margarethe A. Cooper 15 Diseases produced by Clostridioides difficile 267 Santiago S. Diab and Francisco A. Uzal 16 Disease caused by Clostridium colinum: ulcerative enteritis of poultry and other avian species 291 Agustin Rebollada-Merino and Francisco A. Uzal 17 Diseases produced by Thomasclavelia spiroformis 301 Laura M. Tuomisto and Francisco A.
Uzal 18 Clostridial abomasitis 309 John F. Prescott and Russell S. Fraser Part IV Clostridial histotoxic infections 325 19 Blackleg 327 Camila C. Abreu and Francisco A. Uzal 20 Gas gangrene 345 Rodrigo O. S. Silva, Francisco A. Uzal, Carlos A.
Oliveira Junior, and Francisco C. F. Lobato 21 Gangrenous dermatitis in poultry 359 Mauricio A. Navarro, Francisco A. Uzal, and H. L. Shivaprasad 22 Bacillary hemoglobinuria 369 Mauricio A. Navarro, Fernando Dutra-Quintela, and Francisco A.
Uzal 23 Infectious necrotic hepatitis 381 Mauricio A. Navarro and Francisco A. Uzal 24 Tyzzer disease 387 Karina C. Fresneda, Juan A. García, and Francisco R. Carvallo-Chaigneau Part V Clostridial neurotoxic infections 401 25 Tetanus 403 Michel R. Popoff and Francisco A. Uzal 26 Botulism 415 Caroline Le Maréchal, Fabrizio Anniballi, Luca Bano, Martin B.
Dorner, Miriam Koene, Christelle Mazuet, Christian Seyboldt, and Tom Van Nieuwenhuysen 27 Diseases caused by other clostridia producing neurotoxins 451 John F. Prescott and Michel R. Popoff Part VI Animal clostridial diseases as zoonosis and animals as reservoir of human clostridial pathogens 455 28 Clostridial infections and one health 457 Francisco A. Uzal and Michel R. Popoff References 466 Index 475.