Contributors Preface 1 The Pathogenic clostridia 1 Taxonomic relationships among the clostridia 2 General physiologic and virulence properties of the pathogenic clostridia 3 Brief description of animal pathogenic clostridia 2 Toxins produced by the pathogenis clostridia 4 Toxins of histotoxic clostridia: Clostridium chauvoei, Clostridium septicum, Clostridium novyi and Paeniclostridium sordellii 5 Toxins of Clostridium perfringens 6 Toxins of Clostridioides difficile 7 Clostridium botulinum and Clostridium tetani neurotoxins 3 Clostridial infections of the gastrointestinal system 8 Diseases produced by Clostridium perfringens type A 9 Diseases produced by Clostridium perfringens type B 10 Diseases produced by Clostridium perfringens type C 11 Diseases produced by Clostridium perfringens type D 12 Diseases produced by Clostridium perfringens type E 13 Diseases produced by Clostridium perfringens type F 14 Diseases produced by Clostridium perfringens type G 15 Diseases produced by Clostridioides difficile 16 Disease caused by Clostridium colinum: Ulcerative enteritis of poultry and other avian species 17 Diseases produced by Clostridium spiroforme 18 Clostridial abomasitis of ruminants 4 Clostridial histotoxic infections 19 Blackleg 20 Gas gangrene 21 Gangrenous dermatitis of poultry 22 Bacillary hemoglobinuria 23 Infectious necrotic hepatitis 24 Tyzzer disease 5 Clostridial neurotoxic infections 25 Tetanus 26 Botulism 27 Diseases caused by other clostridia producing neurotoxins 6 Animal clostrifial diseases as zoonosis and animals as reservoir of human clostridial pathogens 28 Animal clostrifial diseases as zoonosis and animals as reservoir of human clostridial pathogens.