1. The Classification of Depression: Embracing Phenotypic Heterogeneity in the Era of the RDoC 2. Incidence, Prevalence, and Global Burden of Depression 3. The Role of Environmental and Psychosocial Factors in Depression 4. Gene-Environment Interactions and Epigenetic Mechanisms in Depression 5. Pathophysiology of Cognitive Impairment in Depression 6. Anhedonia in Depression: Mechanisms, Assessment, and Therapeutics 7. The Neurotrophic Hypothesis of Depression Revisited: New Insights and Therapeutic Implications 8.
The Monoamine Hypothesis of Depression Revisited: Could It Lead to Mechanistically Novel Antidepressant Strategies? 9. Neuro-Immune Interactions in Depression: Mechanisms and Translational Implications 10. The Hypothalamic-Pituitary-Adrenal Axis in Depression: Molecular Regulation, Pathophysiological Role, and Translational Implications 11. Intracellular Signalling Pathways Implicated in the Pathophysiology of Depression 12. The Long-Lasting Neurobiological Scars of Early-Life Stress: Implications for the Neurobiology of Depression 13. Molecular, Cellular, and Circuit Basis of Depression Susceptibility and Resilience 14. More Than a Gut Feeling: Emerging Roles of the Microbiome in the Pathophysiology and Treatment of Depression 15. Optogenetics: Illuminating the Neural Circuits of Depression 16.
Mitochondrial Dysfunction and Oxidative Stress: Relevance to the Pathophysiology and Treatment of Depression 17. Obesity and Depression: Shared Pathophysiology and Translational Implications 18. Neurobiology of Antidepressant-Induced Weight Gain 19. Depression and Cardiovascular Risk: Epidemiology, Mechanisms, and Implications 20. Poststroke Depression: Pathophysiology and Treatment Strategies 21. Is Depression Associated with Accelerated Aging? Mechanisms and Implications 22. Relationship Between Complicated Grief and Depression: Relevance, Etiological Mechanisms, and Implications 23. Understanding the Neurobiology of Depression through Structural Neuroimaging 24.
A Neural Circuit-Based Model for Depression Anchored in a Synthesis of Insights from Functional Neuroimaging 25. Could Depression Be Preventable? Evidence and Perspectives 26. Treating Depression in the Era of Precision Medicine: Challenges and Perspectives 27. Neurobiological Aspects of Functional Recovery in Major Depressive Disorder 28. Diet and Depression: From Epidemiology to Novel Therapeutics 29. Physical Activity and Exercise as a Treatment of Depression: Evidence and Neurobiological Mechanism 30. Antidepressants and Suicidality--Controversies and Possible Mechanisms 31. Altered GABAergic Function, Cortical Microcircuitry, and Information Processing in Depression 32.
Implications of Pharmacogenomics in Depression Pathophysiology and Treatment 33. Novel Neuromodulatory Approaches for Depression: Neurobiological Mechanisms 34. Electroconvulsive Therapy for Depression: Neurobiological Mechanisms 35. Putative Mechanism of Action for Vagus Nerve Stimulation as Therapeutic for Depression 36. Deep Brain Stimulation: Mechanisms Underpinning Antidepressant Effects 37. Novel Therapeutic Targets for Major Depressive Disorder 38. The Search for Rapid Acting Antidepressants: Research Synthesis and Perspectives 39. Neurobiology of Child and Adolescent Depression 40.
Neurobiology of Depression in Women 41. Biological Basis of Late-Life Depression 42. Advances in Early Age Depression 43. What Makes Ketamine a Better Antidepressant? 44. Neurobiology of Suicide in Depression 45. Neurobiology of Depression as a Risk Factor for Alzheimer''s Disease 46. Neurobiology of Treatment-Resistant Depression 47. Understanding the Mechanism of Action of Psychedelics as Therapy for Depression 48.
Neurobiology of Bipolar Depression 49. Computational Models in Depression 50. Neurobiology of Psychotherapy for Depression.