Maintaining its status as the gold standard in medicinal chemistry education, Foye's Principles of Medicinal Chemistry, 9th Edition , presents a renewed focus on the fundamental concepts that form the backbone of this critical discipline. This latest edition, helmed by new senior editors Marc Harrold and Kim Beck, continues the text's legacy of excellence while streamlining content for today's pharmacy students and practitioners. Expert contributions from experienced educators, research scientists, and clinicians clarify the chemical basis of drug action, emphasizing the structure-activity relationships, physicochemical-pharmacokinetic properties, and metabolic profiles of the most commonly used drugs. UPDATED! Focused content emphasizes essential information in an ideal format for contemporary PharmD curricula. UPDATED! Drug information equips students with the latest developments in drug discovery, structure optimization and clinical use. Clinical Significance testimonials provide a clinician's view of the relevance of medicinal chemistry to practice. End-of-Chapter exercises provide valuable self-assessment opportunities and reinforce key concepts.