Part I. Conceptual and diagnostic issues.- 1. Current criticism on DSM-5 and future perspective on DSM-6 in major depression.- 2. Diagnostic biomarkers and biogoical classification in major depression.- 3. Neural circuit taxonomy and precision psychiatry in major depression.
- 4. Lifelog and Voice Informed Forecast and Detection for diagnosis of major depression.- 5. Differentiation of major depression from bipolar depression.- 6. Rethinking the treatment resistant depression.- 7. Understanding psychotic depression.
- Part II. Etiological and neurobiological issues.- 8. Complex role of serotonin-dopamine-glutamate receptors in major depression.- 9. New concept of gene-environment interections and epigenetics in major depression.- 10. Early life stress in HPA axis and MR/GR receptors in the development of major depression.
- 11. Molecular, structural and functional neuroimaging in major depression.- 12. Chronic inflammation and neuroprogression in the pathophysiology in major depression.- 13. Understanding the connection between the gut-brain axis and major depression.- 14. Different biological mechanisms and treatments of depressive subtypes.
- Part III. Symptomatic and clinical issues.- 15. Reconceptualization of anhedonia as a crucial symptom in major depression.- 16. Chronic pain and major depression: shared psychological and neurobiological mechanism.- 17. Current knowledge of cognitive dimension of major depression.
- 18. Suicide behavior as a distinct psychobiology in major depression.- 19. Directional relationship between obesity and major depression.- 20. Gender differences in disease progression in major depression.- 21. Current knowledge of postpartum depression.
- 22. Neurobiology and risk factors in late life depression.- Part IV. Therapeutic issues.- 23. New antidepressant development in the treatment of depression.- 24. Chronotherapy in the treatment of major depression.
- 25. Psychedelics: future therapeutics in major depression?.- 26. Novel therapeutic strategies for treatment-resistant depression(TRD).- 27. New clinical applications of neurostimulation in major depression.- 28. Promising digital therapeutics in the treatment of major depression.
- 29. Novel psychological interventions in the treatment of major depression.- 30. Personalized intergrative treatment in major depression.