I Introduction.- 1 Historical perspective on the evolution of the techniques and role of the neurosurgeon.- 2 Embryology: Skull growth, posterior fossa growth: what is important for the neurosurgeon.- 3 Genetics of craniosynostoses : what is important for the neurosurgeon.- 4 Animal models : what is important for the neurosurgeon.- 5 Analysis of postnatal skull shape and brain growth: what is important for the neurosurgeon.- II Clinical aspects.- 6 Clinical diagnosis: what is important for the neurosurgeon.
- 7 Sagittal sutures synostosis: key points for the neurosurgeons, management principles (diagnosis, surgical principles and their rationale, timing).- 8 Metopic sutures synostosis: key points for the neurosurgeons, management principles (diagnosis, surgical principles and their rationale, timing).- 9 Coronal sutures synostosis: key points for the neurosurgeons, management principles (diagnosis, surgical principles and their rationale, timing).- 10 Sphenopalatine synostosis: key points for the neurosurgeons, management principles (diagnosis, surgical principles and their rationale, timing).- 11 Lambdoid sutures synostosis: key points for the neurosurgeons, management principles (diagnosis, surgical principles and their rationale, timing).- 12 Multiple sutures synostosis: key points for the neurosurgeons management principles (diagnosis, surgical principles and their rationale, timing).- III CSF and hemodynamics alterations in craniosynostoses.- 13 Hydrocephalus.
- 14 Pericerebral effusions.- 15 Cerebral perfusion in craniosynostoses .- 16 What perfusion explorations ? US, NIRS, TCD, ASL etc.- 17 Venous anomalies and craniosynostosis.- 18 Craniocerebral disproportion and raised ICP in craniosynostoses.- 19 Cerebellar tonsils herniation in craniosynostoses. 20 Syringomyelia in craniosynostoses.- 21 Surgical indications: when is surgery necessary.
- 22 Controversies in the indications for surgery (surgery vs no surgery, esthetic indication vs functional indication .).- III The multidisciplinary team and the neurosurgeon.- 23 The role of the neurosurgeon in the multidisciplinary team.- 24 Antenatal diagnosis.- 25 What to ask to the radiologist in craniosynostoses?.- 26 What to ask to the ENT in craniosynostoses?.- 27 What to ask to the ophthalmologist in craniosynostoses?.
- 28 What to ask to the maxillofacial surgeon in craniosynostoses?.- 29 What to ask to the orthodontist in craniosynostoses?.- 30 What to ask to the genetist in craniosynostoses?.- 31 What to ask to the pediatrician in craniosynostoses.- 32 What to ask to the psychologist, Psychological aspects.- IV Technical aspects.- 33 Role of 3D volummetry and 3D planning.- 34 Anesthesiological issues: what the neurosurgeon should.
- 35 Hemostasis and transfusion in craniosynostoses surgery.- 36 Osteotomy principles, tools and hardware presentation.- 37 Resorbable and non resorbable materials in in craniosynostoses surgery.- V Surgical procedures.- 38 Fixed Posterior vault remodeling.- 39 Posterior vault distraction.- 40 Anterior vault remodeling.- 41 Spring assisted vault remodeling.
- 42 Endoscopic approaches.- 43 Role of the post-operative helmet.- 44 technical tips for surgery in older children.- 45 Controversies in the type of surgery (What technique in which case ? the heterogeneity of the management of craniosynostoses minimally invasive vs total vault etc ).- VI Surgical Steps(How I do it).- 46 surgery for sagittal suture synostosis: key points for the neurosurgeons.- 47 Endoscopic.- open vault.
- 48 old children.- 49 distraction.- 50 Spring.- VII surgery for metopic suture synostosis: key points for the neurosurgeons.- 51 open vault.- 52 Endoscopic-surgery for coronal suture synostosis: key points for the neurosurgeons.- 53 open vault.- 54 Endoscopic.
- 55 distraction.- 56 surgery for lambdoid suture synostosis: key points for the neurosurgeons.- 57 surgery for multiple sutures synostosis: key points for the neurosurgeons (strategy and timing of the procedures).- 58 Foramen magnum decompression in craniosynostosis.- 59 role of ETV in craniosynostoses.- 60 VP shunt in craniosynostoses.- 61 Post-operative management.- VIII RESULTS.
- 62 What evaluation tools in craniosynostoses ?.- 63 Mortality, morbidity and complications avoidance.- 64 Cognitive aspects and outcome.- 65 Functional results.- 66 Impact of genetics on the outcome.- 67 Quality of life.- 68 Impact of post-surgical helmet therapy on cognitive outcomes.- 60 Long Follow-up results.