In this issue of Thoracic Surgery Clinics , guest editors Drs. Mara B. Antonoff and Smita Sihag bring their considerable expertise to the topic of Pulmonary Metastasectomy . Top experts provide articles on the most common pulmonary metastasectomies (colorectal cancer, renal cell carcinoma, sarcoma, melanoma, and head and neck cancer), along with articles on hybrid approaches to local management, transcontinental differences in management, disparities, quality of life, and reoperative pulmonary metastasectomy. Contains 13 relevant, practice-oriented topics including hybrid approaches to local management of pulmonary metastatic disease; role of metastasectomy for tissue acquisition for TIL harvest, biomarker/genomic testing; impact of metastasectomy on quality of life; disparities in pulmonary metastasectomy; workup, indications, and guiding principles of selection for pulmonary metastasectomy; and more. Provides in-depth articles on pulmonary metastasectomy , offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.