In this issue of Urologic Clinics of North America , guest editor Dr. Isaac Yi Kim brings his considerable expertise to the topic of Management of Advanced and Metastatic Prostate Cancer . Although prostate cancer is generally considered curable, advanced and metastatic prostate cancer remain a challenge for urologists and oncologists. In this issue, top experts discuss pelvic lymph node dissection; radiotherapy for high-risk prostate cancer; managing clinical N1 prostate cancer; managing biochemical recurrence after definitive local therapy; and more. Contains 14 relevant, practice-oriented topics, including imaging-based diagnostics and therapeutics in advanced prostate cancer; surgical management of high-risk prostate cancer; neoadjuvant and adjuvant therapies for high-risk prostate cancer; recent advances in understanding the biology of castration-resistant prostate cancer; treatments on the horizon for men with advanced prostate cancer; and more Provides in-depth clinical reviews on management of advanced and metastatic prostate cancer , offering actionable insights for clinical practice Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.