PART ONE: INTRODUCTION TO STEM CELLS 1. Why Stem Cell Research? Advances in the Field 2. 'Stemness': Definitions, Criteria, and Standards 3. Pluripotent Stem Cells from Vertebrate Embryos: Present Perspective and Future Challenges 4. Embryonic Stem Cells in Perspective 5. The Development of Epithelial Stem Cell Concepts PART TWO: BASIC BIOLOGY/MECHANISMS 6. Stem Cell Niches 7. Mechanisms of Stem Cell Self-Renewal 8.
Cell Cycle Regulators in Stem Cells 9. How Cells Change Their Phenotype PART THREE: TISSUE AND ORGAN DEVELOPMENT 10. Differentiation in Early Development 11. Stem Cells Derived from Amniotic Fluid 12. Stem and Progenitor Cells Isolated from Cord Blood 13. The Nervous System 14. Sensory Epithelium of the Eye and Ear 15. Epithelial Skin Stem Cells 16.
Hematopoietic Stem Cells 17. Peripheral Blood Stem Cells 18. Multipotent Adult Progenitor Cells 19. Mesenchymal Stem Cells 20. Skeletal Muscle Stem Cells 21. Stem Cells and the Regenerating Heart 22. Cell Lineages and Stem Cells in the Embryonic Kidney 23. Adult Liver Stem Cells 24.
Pancreatic Stem Cells 25. Stem Cells in the Gastrointestinal Tract PART FOUR: METHODS 26. Induced Pluripotent Stem Cells 27. Embryonic Stem Cells: Derivation and Properties 28. Isolation and Maintenance of Murine Embryonic Stem Cells 29. Approaches for Derivation and Maintenance of Human Embryonic Stem Cells: Detailed Procedures and Alternatives 30. Derivation and Differentiation of Human Embryonic Germ Cells PART FIVE: APPLICATIONS 32. Neural Stem Cells - Therapeutic Applications in Neurodegenerative Diseases 33.
Adult Progenitor Cells as a Potential Treatment for Diabetes 34. Burns and Skin Ulcers 35. Stem Cells and Heart Disease 36. Stem Cells for the Treatment of Muscular Dystrophy 37. Cell Therapy for Liver Disease: From Hepatocytes to Stem Cells 38. Orthopedic Applications of Stem Cells 39. Embryonic Stem Cells in Tissue Engineering PART SIX: REGULATION AND ETHICS 40. Ethical Considerations 41.
Overview of the FDA Regulatory Process.