This volume in the Cell Biology and Translational Medicine series continues to explore the promising applications of stem cells in regenerative medicine. The topics presented in this volume address aspects of stem cell regeneration, both in health and disease. The volume looks at recent developments in bone, dentistry, epigenetic regulation in stem cell biology and regeneration. A goal of the series continues to be to highlight timely, often emerging topics and novel approaches that can accelerate the utility of stem cells in regenerative medicine.