Advances in Research on Pediatric Gender Affirming Healthcare summarizes recent and ongoing research efforts across global regions in the field of pediatric gender affirming healthcare. Contributors from diverse backgrounds and experience come together with informative scientific findings in an effort to reduce bias and better meet the needs of this marginalized group of young people. The book begins with an overview of the current and historical context in which research and clinical practice of pediatric gender affirming care occurs. It goes on to cover gender development and developmental pathways, risk and resilience among transgender and gender diverse youth, and an overview of healthcare and barriers to access before exploring specific care models for pediatric gender affirming healthcare. The final chapter summarizes the current state of the research, highlights key gaps in scientific knowledge, and asserts a call to action to researchers in the field to answer principal questions with high-quality research methods. This book highlights unique considerations for researchers and healthcare providers of transgender and gender diverse youth seeking healthcare in the context of minority stress and political divide.