Part I: The amyloid transformation 1. The hypothesis - the biochemistry of amyloids 2. Three examples of different scenarios of amyloid transformation Part II: Role of local environment in proteins structurization 3. Water environment 4. Membrane environment 5. General universal form to express the external force field Part III: Local environment representation in programs oriented on protein structure prediction 6. Presentation of protocol for In Silico folding simulation Part IV: Specificity of secondary structure in amyloids 7. Analysis of secondary structure specificity as it appears in amyloids Part V: The complete spectrum of environment influence (external force field) on protein folding 8.

The examples of protein representing the micelle-like construction 9. The examples of proteins with participation of external force field in moderate degree 10. The trans-membrane proteins as examples of high influence of local environment on protein structurization 11. Enzymes - their protein body - as objects delivering the local external force field for catalytic reaction 12. Folding in assistance of chaperonin, chaperon, prefoldin - analysis as expressed by FOD-M model Part VI: Alternative models for amyloid interpretation 13. Alternative models.