An overview of ADAMTS proteases.- Overview of the Roles of ADAMTS1 in Ovarian Biology.- Methods for Defining the Role of ADAMTS1 in the Ovary.- Modeling Aspects of Human Placental Development with Trophoblast Stem Cells.- Exploring The Role of ADAMTS4 Expression in Atherosclerosis.- Method for Generation ofadamtsl4knock-out zebrafish lines using CRRISPR/Cas9 system.- Assay for neurocan-degrading activity of ADAMTS12 metalloprotease .- Generatingadamts13-/-Zebrafish via CRISPR/Cas9 Gene Editing.
- Determining ADAMTS13 conformation for the diagnosis of immune thrombotic thrombocytopenic purpura and prediction of relapse.- Methods for studying the role of ADAMTS13 in angiogenesis.- Assays for Plasma ADAMTS13 Activity and Inhibitors using recombinant FRETS-VWF73 peptide .- A Vortex-Shear Based Assay for Cleavage of Multimeric VWF by ADAMTS13.- Deep protease profiling to define the substrate specificity of ADAMTS proteases .- Microfluidic shear-based assay for assessing ADAMTS13 activity under flow- Optical-Tweezers Single-Molecule Assay for ADAMTS13-Mediated Proteolysis of the von Willebrand Factor A2 Domain.- Method for Assessing Inhibition Kinetics of Autoantibodies Against ADAMTS13 in Immune Thrombotic Thrombocytopenic Purpura.- Hydrogen Exchange Mass Spectrometry for Mapping Antibody Binding Sites and Conformational Dynamics of ADAMTS13.
- Treating Immune Thrombotic Thrombocytopenic Purpura with Therapeutic Plasma Exchange.- Molecular Dynamics Simulations with NAMD and Trajectory Analysis .- Treating immune-mediated thrombotic thrombocytopenic purpura by Caplacizumab .- Treating Immune Thrombocytopenic Purpura by Immunosuppressive Agents.