The 21st century has seen the rise and resurgence of viral threats that have reshaped global health, economies, and daily life. From seasonal influenza to unprecedented pandemics like COVID-19, the urgency for rapid, accurate, and scalable virus detection has never been greater. Sensor technologies have emerged as vital tools in this landscape, enabling early diagnosis, environmental monitoring, and real-time health surveillance. This book offers a comprehensive, multidisciplinary exploration of sensor-based virus detection technologies. It brings together leading voices from academia and industry to cover a wide range of topics from foundational detection principles to cutting-edge innovations like CRISPR-based biosensors, wearable diagnostics and AI-powered data analysis. Designed for researchers, engineers, clinicians, and policymakers, this volume provides both a deep dive into current technologies and a forward-looking perspective on the future of virus detection. It is an essential resource for anyone engaged in the science and strategy of global health preparedness.