The central question explored in this volume is: How is humor multimodally produced, perceived, responded to, and negotiated? To this end, it offers a panorama of linguistic research on multimodal and interactional humor, based on different theoretical frameworks, corpora, and methodologies. Humor is considered as an activity that is interactionally achieved, regardless of whether the interaction in which it is embedded is face-to-face, computer-mediated, with a human or a robot, oral or written. The aim is to analyze both the linguistic resources of the participants (such as their lexicon, prosody, gestures, gazes, or smiles) and the semiotic resources that social networks and instant messaging platforms offer them (such as memes, gifs, or emojis).