ContentsPART I INTRODUCTION AND OVERVIEW1 Why a handbook on regions and transformative innovation policy? 2Sylvia Schwaag Serger and Luc Soete2 Introducing the chapters: an overview 9Slavo RadosevicPART II CONCEPTUAL CHALLENGES OF REGIONAL TRANSFORMATIVEINNOVATION POLICY3 Enhancing the sustainability dimension in smart specialisation strategies:towards a framework for reflexive policy practice 29Michal Miedzioski, Lars Coenen and Henrik Larsen4 Exploring the governance challenge of regional transformative innovationpolicies: a metagovernance perspective 53Ainhoa Arrona and Edurne Magro5 Transforming regions, change agency, and policy 69Markus Grillitsch6 From problems to opportunities: a place-based approach to transformativeinnovation policy 87Elvira UyarraPART III REGIONS IN THE TRANSFORMATION TO SUSTAINABILITY7 From smart specialisation to smart transformation - (how) do regionsintegrate transformative intentions in regional innovation priorities? 103Sofia Avdeitchikova- and Anders Olsson8 Embedding sustainability transitions in Catalonia's smart specialisationstrategy 120Tatiana Fernández Sirera and Michal Miedzioski9 Conditions for sustainability transitions in Germany's peripheral regions: adifferentiated view on regional change agency 137Henning Kroll, Max Roessler, Valeria Maruseva and Daniel Schiller10 Sustainable foodscapes: the transformation of public food systems 155Kevin Morgan11 Unravelling innovation transition traps: the imperative of collective action 171Peter Wostner, Anze Burger, Iztok Palcic and Sonja Slander Wostner12 Contrasting pathways to regional transformative policies: bottom-upapproaches of a leading and latecomer region in Czechia 190Jirí Blazek, Viktor Kvetoo, Vojtech Kadlec and Jan PojslPART IV TRANSFORMATIVE REGIONAL INNOVATION POLICY GOES GLOBAL13 Public-private partnerships and regional transformative innovation policyin the US 211Monica Novoa and Paige Clayton14 Innovation and the states: the regional manifestations of the EndlessFrontier in the US Rust Belt 229Ben Armstrong and Dan Traficonte15 Regional entrepreneurial mentoring networks as transformative innovationpolicy: insights from a semi-peripheral high tech hub 242Darius Ornston and Isabelle Watkinson16 The evolution of Korea's regional innovation system: the case of DaedeokInnopolis 257Hye-Ran Hwang and Jae-Yong Choung17 Integrating 'Society 5.0' and regional revitalisation: Japan's path totransformative innovation 278Michiko Iizuka and Takayuki Hayashi18 Latin America and transformative innovation policy 296Matias Ramirez19 The urban transformation of Medellín: confluence of innovation processesand transformation limits 309Jorge Robledo Velásquez, Walter Lugo Ruiz Castañeda and MaríaLuisa Villalba Morales20 Strengthening inclusive innovation systems: analysis of the Western Cape'seconomic development activities 328Sara Grobbelaar21 Green goals, strategic actions: China's experience with transformativeinnovation policy 348Hannah Yi Wei22 Regional transformative innovation policy towards green development inChina 368Zhen Yu and Lan Xue23 Reorienting STI policy for transformative change: lessons from and forIndia 381Soutrik Basu24 The less-than-one percent: how a few firms shape regional capabilities inIndia 397Nanditha Mathew and Emanuele PugliesePART V CONCLUSIONS AND ISSUES FOR FURTHER RESEARCH25 Transformative regional innovation policy globally: state of the art andissues for future research 425Slavo Radosevic26 Epilogue 441Sylvia Schwaag Serger and Luc Soete.